Cell Characteristics |
Célle (Menstrual
Stromal Cells) |
BM MSC (Bone Marrow
Mesenchymal Cells) |
Cell Collection Procedure |
Non-invasive menstrual cup similar to insertion
of a tampon |
Harvest bone marrow in the OR mobilized adult
peripheral blood |
Cell Morphology |
stromal, mesenchymal-like, spindle-shaped
in culture |
stromal, mesenchymal-like, spindle-shaped
in culture (4) |
Cell Surface Markers associated with mesenchymal
cells |
CD29, CD44, CD73, CD90, CD105, CD166
MHC I+ MHC II- |
CD29, CD44, CD73, CD90, CD105, CD166
MHC I+ MHC II- (1)(3) |
Markers associated with embryonic stem cells |
SSEA-4, Oct-4 |
none |
Differentiation capability |
Neural, Cardiogenic, Chondrogenic, Adipogenic,
Osteogenic |
Chondrogenic, Adipogenic, Osteogenic (2) |
MLR |
Cells demonstarted a weak stimulatory response
which suggests potential use in first-degree relatives |
Do not elicit alloreactive lymphocyte proliferative
responses (1) |
Karotype |
Normal karyotype |
Normal Karyotye (3) |